Table 1.

Effect of probiotic treatment on parameters of colitis in the 3% dextran sulphate sodium (DSS) moderate to severe colitis model.

Treatment	Macroscopic score	Histological score	Colon length (cm)	Weight gain/loss (g)*	Survival rate
PBS (control)	5·9 ± 0·6	12·3 ± 1·1	6·2 ± 0·3	0·8 ± 0·5	8/10
LGG wild-type	6·9 ± 0·3	12·6 ± 0·8	5·4 ± 0·3	−0·5 ± 0·7	8/10
dltD mutant	4·1 ± 0·6†	12·1 ± 0·5	5·9 ± 0·1	1·4 ± 0·3†	10/10

All data represent mean ± standard error of the mean [n = 8 for phosphate-buffered saline (PBS) and Lactobacillus rhamnosus GG (LGG) wild-type group, n = 10 for dltD mutant group]. Mice that did not survive were not included in the analysis of the colitic parameters.

^*Weight gain/loss was determined by calculating the difference in weight between day 28 (end of the experiment) and day 0 (start of the experiment). Comparison between all groups has been calculated; only significant differences are marked.

^†P < 0·05 between dltD-mutant and LGG wild-type-treated group.