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Model of the KIF13B-CENTA1 transport machinery. (A) Structural model of KIF13B/CENTA1/IP4 complex. Electrostatic potential surface of centaurin molecules was calculated from IP4-bound CENTA1 coordinate. KIF13B-FHA domains are shown as ribbons. IP4s bound to the PH domains were modeled from the CENTA1/IP4 complex structure. The C-terminal helix of CENTA1 that appeared upon FHA or IP4 binding is shown as a blue ribbon. (B) Assembly of KIF13B/CENTA1 transport machinery.
