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. 2010 Nov 8;107(47):20571–20575. doi: 10.1073/pnas.1015281107

Fig. 1.

Fig. 1.

IGF1 deficits and growth parameters in CF pigs. (A) CF pigs (n = 5) gained less weight than did non-CF pigs (n = 7). Data are mean ± SE. (B) CF pigs (n = 5) had reduced plasma IGF1 levels compared with non-CF pigs (n = 7). Differences became more exaggerated over time. CF pigs, two females and three males; non-CF pigs, three females and four males. Data are for individual animals; line represents mean ± SE. *P = 0.003 compared with non-CF pigs at 8–12 wks and P = 0.016 at 15–25 wks versus non-CF pigs. (C) Plasma IGF1 levels in newborn piglets 6–12 h old indicated that CF piglets (five females and four males) had significantly reduced plasma IGF levels relative to non-CF piglets (seven females and four males); P = 0.005. Data are for individual animals; line represents mean ± SE. (D) Average birth weight was lower, but not statistically different, in CF compared with non-CF piglets (P = 0.12). (E) Humerus length of newborn CF piglets was shorter than that of non-CF animals (P = 0.04). For D and E, CF, 7 females and 11 males; non-CF, 7 females and 10 males. Data are mean ± SE.