Table 1.

miRs differentially expressed between HB subtypes

P value	FDR	C2/C1 ratio	Mature miR	Function
2.0e-05	6.6e-04	2.62	miR-373	Tumor invasion, growth under hypoxia
4.0e-04	0.0059	2.57	miR-369
3.3e-05	8.5e-04	2.29	miR-371–5p
2.9e-04	0.0049	1.57	miR-128a
4.3e-04	0.0062	1.52	miR-31	Antimetastatic
8.9e-05	0.0018	0.55	miR-23a	Differentiation, glutamine metabolism
4.3e-05	0.0010	0.55	miR-342–3p	Down-regulated in colon cancer
7.2e-05	0.0016	0.54	miR-27a	Fat metabolism regulation
2.2e-04	0.0038	0.51	miR-30e	Sumoylation
1.2e-05	4.9e-04	0.50	miR-23b	Glutamine metabolism
3.0e-05	8.5e-04	0.46	let-7g	Differentiation, tumor suppressor
1.7e-06	8.1e-05	0.36	miR-16	Proapoptotic
1.9e-05	6.6e-04	0.35	miR-125b	Tumor suppressor, tissue differentiation
<1e-07	<1e-07	0.33	miR-26a	Cell cycle inhibitor, TGF-β and Akt pathways
3.2e-04	0.0049	0.32	miR-10a	Ribosomal protein translation
1e-06	5.3e-05	0.32	let-7f
6e-07	3.7e-05	0.28	let-7c	Differentiation, tumor suppressor
2e-07	2.1e-05	0.27	let-7d
1e-07	1.4e-05	0.25	let-7a	Differentiation, tumor suppressor
<1e-07	<1e-07	0.20	miR-100	Mitotic check point, mTOR signaling

miRs repressed by Myc are shown in bold. FDR, false discovery rate. Fold change cutoff = 1.5; P value cutoff <5.0e-04.