Table 2.
Sister chromatid exchanges (SCE) in spermatogonial cells of mice treated with chamomile essential oil (CEO) and daunorrubicin (DAU).
| Agent | Dose (mg/kg) | SCE ± S.D. | Inhibition (%) |
|---|---|---|---|
| Controla | 0 | * 1.90 ± 0.40 | |
| CEO | 500 | * 2.36 ± 0.44 | |
| DAU | 10 | 11.21 ± 1.38 | |
| CEO+DAU | 5+10 | * 6.78 ± 1.05 | 47.5 |
| CEO+DAU | 50+10 | * 5.44 ± 0.33 | 61.9 |
| CEO+DAU | 500+10 | * 2.50 ± 0.31 | 93.5 |
a
Corn oil (0.1 mL/mouse);
*
Statistically significant difference with respect to the group treated with DAU. ANOVA and Student t tests, p < 0.05. % inhibition = 100 − (SCE of CEO + DAU - SCE control/SCE of DAU-SCE control) × 100.