Table 7.

Results of Logistic Regression Analysis Examining Influence of Clinical Factors on In-Hospital Death

	Odds value	95% Confidence interval	P value
Demographics
Male sex	0.87	0.55, 1.37	0.54
Age ≥ 70 years	3.81	2.22, 6.54	<0.0001
APACHE II1 ≥ 20	5.24	3.23, 8.53	<0.0001
In intensive care unit	3.53	1.78, 7.02	0.0003
Days from admission to treatment ≥ 10	1.32	0.76, 2.27	0.32
Maximum temperature ≥ 38.5°C	0.31	0.18, 0.54	<0.0001
Maximum white blood cell ≥ 20,000/mm3	1.18	0.73, 1.90	0.50
Medical conditions
Corticosteroid use	1.32	0.65, 2.64	0.44
Solid organ allograft	0.47	0.14, 1.57	0.22
Diabetes mellitus	1.15	0.69, 1.91	0.59
Cardiac disease	2.12	1.26, 3.57	0.0048
Malignant disease	3.41	1.97, 5.93	<0.0001
Baseline pulmonary disease	1.54	0.85, 2.81	0.16
Ventilator dependence	1.78	0.87, 3.68	0.11
Liver disease	2.84	1.42, 5.68	0.0032
Dialysis dependence	2.39	1.25, 4.56	0.0084
Infection with resistant organism2	1.39	0.83, 2.30	0.21
Interaction terms3
Resistant organism + solid organ allograft	5.18	1.60, 16.8	0.0061

¹At time of diagnosis of intra-abdominal infection.

²Includes P. aeruginosa, S. maltophilia, Acinetobacter spp., methicillin-resistant S. aureus, coagu-lase-negative staphylococci, vancomycin-resistant enterococci, or any fungi.

³Tests for synergistic effect of one or more terms in combination, independent of individual contribution of each.

APACHE = Acute Physiology and Chronic Health Evaluation.

c statistic = 0.887; R² = 0.226.