. Author manuscript; available in PMC: 2010 Dec 6.

Published in final edited form as: Transplant Proc. 1993 Feb;25(1 Pt 1):628–634.

Table 3.

Incidence, FK 506 Trough Plasma Levels, General Characteristics, and Outcome of the Late Onset Nephropathy

	Prior Early Onset	No Prior Nephropathy
No. patients (%)	59 (17.4%)	63 (18.6%)
FK 506 levels (ng/mL)
At start onset	1.4 ± 1.1	1.6 ± 1.1
At end onset	0.8 ± 0.7	0.9 ± 0.7
Median time of occurrence (d after OLTx)	98	130
Median duration of onset (d)	168	159
No. patients requiring dialysis	5 (8.5%)	10 (15.9%)
Outcome [no. patients (%)]
Deaths during the onset	6 (10.2%)	8 (12.7%)
Ongoing nephropathy	32 (54.2%)	35 (55.5%)
Complete recovery	21 (35.6%)	20 (31.8%)

The 10 patients that developed a long-lasting nephropathy progressing from early onset without recovery (persistent nephrotoxicity) are not included (see text).