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. Author manuscript; available in PMC: 2011 Nov 16.
Published in final edited form as: Biochemistry. 2010 Oct 22;49(45):9922–9934. doi: 10.1021/bi101008u

Table 5.

Comparison of the active site residues of BsThiM and CgTHI6.

BsThiM CgTHI6
Mg2+ Binding residues Asp 94 Asp 340
Glu 126 Glu 372
Arg 121 Lys 497
Asn 123 Asn 369
AMP-PCP binding residues Thr 168 Thr 416
Gly 169 Gly 417
Glu 170 Glu 418
Thr 191 Gly 459
Gly 195 Ala 463
Ala 196 Ser 464
Tyr 225 Tyr 496
Asp 172 Asp 420
Cys 198 Cys 466
Thiazole binding residues * Met 45 * Met 292
*

Residues from the other chain