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. 2010 Dec;88(6):1081–1087. doi: 10.1189/jlb.0610318

Figure 5. TLR- and IFN-induced Ch25h expression is STAT1-dependent.

Figure 5.

BMDCs (A) and BMMs (B) cultured from 129 WT and stat1−/− mice were stimulated with poly I:C, LPS, IFN-α, IFN-β, or IFN-γ for 6 h, and then, Ch25h transcription was measured by real-time RT-PCR. Bars represent the mean (sd) of the response from three mice/strain for each treatment after normalization to 18S rRNA levels. The differences in expression of Ch25h between 129 WT and stat1−/− for BMMs and BMDCs for each treatment were statistically significant at P < 0.0001 (two-way ANOVA).