Figure 4.

The carbon monoxide dehydrogenase gene clusters. One cluster has orthologs in G. metallireducens (blue arrows), and the other is unique to G. bemidjiensis (pink arrows) and contains an intragenic multicopy nucleotide sequence (pink rectangle). The carbon monoxide dehydrogenase-associated hydrogenase subunits are encoded by cooLXUH, the nickel insertion protein by hypA-2, an accessory protein by cooC, and an iron-sulfur cluster-binding oxidoreductase that transfers electrons from carbon monoxide dehydrogenase to the hydrogenase is encoded by cooF.