Table 2.
List of 17 transcription factor families from ENCODE (UCSC genome web browser) and other published sources, and their detailed methylation profiles in hearts and sperm.
| Motif family | Heart | Sperm |
|---|---|---|
| E2F1 | Hypo-methylated | Hypo-methylated |
| NFY1 | Hypo-methylated | Hypo-methylated |
| YY11 | Hypo-methylated | Hypo-methylated |
| MYCMAX1 | Hypo-methylated | Hyper-methylated |
| NFKB1 | Hypo-methylated | Hyper-methylated |
| AP1 | Hypo-methylated | Hyper-methylated |
| NRSF2 | Hypo-methylated | Neutral |
| SREBP3 | Hypo-methylated | Neutral |
| SRF2 | Hypo-methylated | Neutral |
| STAT4 | Hypo-methylated | Neutral |
| TCF1 | Hypo-methylated | Neutral |
| GATA1 | Neutral | Hyper-methylated |
| NFE21 | Neutral | Neutral |
| OCT5 | Neutral | Neutral |
| SOX5 | Neutral | Neutral |
| EP3005 | Neutral | Neutral |
| TP536 | Neutral | Neutral |
1Yale/UCD/Harvard (ENCODE)
2HudsonAlpha Institute
3Yale/UCD/Harvard/Duke UNC/UT, Genome Institute of Singapore (GIS)
4Yale/UCD/Harvard, GIS
5Lister et al, Nature 2009
6GIS