Table 3.
Candidate Host-association and virulence factors*
| WH6 Gene (PFWH6_) | Host-association or virulence factor | Reported function | Reference |
|---|---|---|---|
| 0718-0737 | T3SS-encoding region | Host-association; secretion apparatus | [15,84] |
| 5796-5812 | T6SS-1-encoding region | Host-association; secretion apparatus | [68,69,73] |
| 3251-3270 | T6SS-2-encoding region | Host-association; secretion apparatus | [68,69] |
| 0824-0827 | Betaine/choline uptake | Osmoprotection | [85] |
| 5455 & 0252 | BCCT Transporter | Choline transport | [86] |
| 5456-5458 | Choline to Betaine | Choline to Betaine conversion | [7] |
| 1723 & 2895 | aprA^ | Alkaline protease A; Insecticidal toxin | [87] |
| 4097/98, 4099, 4100 | tca-d | Insecticidal toxin | [88] |
| 5264, 5082, 3503 & 0070 | katA | Catalase A; H2O2 protection | [89] |
| 0985 - 0996 | Synthesis of Alginate | Exopolysaccharide | [90] |
| 2199 | Synthesis of Levansucrase^ | Exopolysaccharide | [91,92] |
| 4225 | marR | Transcriptional regulator virulence factors | [93] |
| 3833 - 3843 | T2SS-encoding region | Secretion apparatus | [94] |
| 0699 | plc lipase | Phospholipase C; virulence factor | [95] |
| 0396 - 0398 | *TAT-encoding region | Secretion apparatus | [96,97] |
| 4428, 2727, 0116-0120 | Synthesis of mangotoxin | Antimetabolite toxin | [98] |
| 2331-2334 | Synthesis of hydrogen cyanide | Inhibitor of cytochrome c oxidase | [25] |