Figure 4. CD94 is not necessary for clearance of LCMV, vaccinia virus or Listeria infection.
(A) B6 and CD94-deficient mice were infected with 2×105 pfu of LCMV (Armstrong strain). Spleens and livers were analyzed for LCMV titers on the indicated days. (B) B6 and CD94-deficient mice were challenged with 1×105 cfu Listeria monocytogenes. Spleens and livers were analyzed for bacterial burdens three days later. (C) B6 and CD94-deficient mice were challenged with 5×106 pfu vaccinia virus. Spleens and ovaries were analyzed for viral titers seven days later. Graphs represent the average ± s.e.m. of three to five animals per group per time point.