Table 1.
Development of activity based anorexia.
ABA (n=14) | pair-fed (n=13) | naive (n=16) | ||||
---|---|---|---|---|---|---|
baseline | restriction | baseline | restriction | baseline | ad libitum | |
daily activity (revolution) | 5455 ± 806 | 10549 ± 922* | – | – | – | – |
daily food intake (g) suppression % | 16.1 ± 0.7 | 7.3 ± 0.6** | 16.8 ± 0.6 | 7.4 ± 0.6 | 14.7 ± 0.2 | 15.3 ± 0.2 |
54.2±4.2 | 55.5 ± 4 | |||||
body weight (g) weight loss/gain % | 162.9 ± 2.6† | 126.4 ± 2.8 | 176.3 ± 4.1 | 164.9 ± 3.5 | 176.1 ± 2.9 | 199.8 ± 3.2 |
−22.2 ±1.7‡ | −6.4 ±1.2 | +13.5 ± 0.8 |
Values are means ± SE. The baseline refers to the average of the last 3 days values before the restricted food access began for the ABA and the pair-fed groups.
Restricted food access increased mean daily activity compared to mean baseline values, t(13)=5.37, p<0.001.
ABA rats consumed significantly less food during restricted access than their baseline 24 h food intake, t(13)=9.97, p<0.0001.
At baseline running, the ABA rats weighed significantly less than both the pair-fed and naïve rats, F(2, 40)=5.67, p<0.01.
Although consumed the same amount of food during restricted access, the ABA rats lost significantly more percentages of baseline weight than the pair-fed controls at the end of the restriction period, t(25)=7.36, p<0.0001.