Table 2.

Comparison of HIV-HCV coinfected patients without sustained virologic response to matched HCV controls.

Characteristic	HIV - HCV (n=59)1	HCV (n=59)	P
Age (years)1	44 (8)	44 (7.7)	0.99
Male (%)2	71 (58–82)	68 (54–79)	0.84
Caucasian (%)2	15 (7–27)	56 (42–69)	<0.001
AST (U/L)3	74 (50–100)	60 (42–94)	0.37
ALT (U/L)3	80 (51–110)	87 (61–150)	0.081
Treatment naive (%)3	54 (41–67)	19 (10–31)	<0.001
Total HAI inflammation1	6.4 (3)	5.4 (1.8)	0.034
Piecemeal necrosis1	2 (1.4)	1.3 (0.9)	0.014
Lobular inflammation1	2 (1.2)	1.3 (0.91)	<0.001
Portal inflammation1	2.4 (0.99)	2.7 (0.81)	0.13
Knodell fibrosis score (%)2
0	0: 24 (14–37)	0: 24 (14–37)
1	1: 49 (36–63)	1: 49 (36–63)
3	3: 27 (16–40)	3: 27 (16–40)	1
Interval between biopsies (years)1	4.7 (2.3)	5.8 (1.7)	<0.001
Knodell fibrosis change between biopsies1	0.36 (1.2)	0.51 (1.2)	0.48
Change per year in Knodell fibrosis score1	0.12 (0.4)	0.091 (0.29)	0.7

¹Mean (SD);

²Percent (95% confidence interval);

³Median (IQR).