Fig. 1.
Body weight, body composition, and leptin levels after RYGB and sham surgery. A–C, G: Body weight (A), adiposity (B), percent lean mass (C), and plasma leptin levels (G), of outbred Sprague-Dawley rats with either Roux-en-Y gastric bypass surgery (RYGB, filled circles; n = 11) or sham surgery (sham, open circles; n = 11), and non-operated, chow-fed, lean controls (lean, open triangles; n = 10). Body weight in RYGB rats was significantly reduced at all time points after surgery compared with sham-operated controls, but was not significantly different from lean controls. D–F: Body weight (D), adiposity (E), and percent lean mass (F) of genetically select obesity-prone (CD–OP) rats with RYGB (n = 6) or sham-surgery (n = 5). Bars that do not share the same letter are significantly (P < 0.05) different from each other (based on ANOVA and Bonferroni adjusted multiple comparisons).
