Table 2.
Training | Testing | |||
---|---|---|---|---|
SRT | WT | Prior exposure | 42.03 ± 5.75a | 31.47 ± 4.35c |
No- Prior exposure | 63.52 ± 3.02b | 51.65 ± 4.63d | ||
PTH2-R-KO | Prior exposure | 50.15 ± 4.15a | 33.68 ± 5.05c | |
No- Prior exposure | 82.53 ± 5.28b | 54.08 ± 7.52d | ||
ORT | WT | Prior exposure | 54.03 ± 7.26e | 61.07 ± 6.30 |
No- Prior exposure | 68.12 ± 5.66 | 66.44 ± 5.71 | ||
PTH2-R-KO | Prior exposure | 79.65 ± 5.87f | 67.36 ± 4.44 | |
No- Prior exposure | 67.44 ± 5.62 | 62.14 ± 3.68 |
overall effect of the “prior exposure” condition during the training phase of the social recognition test p<0.001;
overall effect of the “prior exposure” condition during the testing phase of the social recognition test p=0.001;
PTH2-R-KO mice have a higher level of exploration compared with WT mice when previously exposed to the experimental conditions p=0.015.