Table 1.
Child-Pugh criteria for assessment of impaired liver function
Points scored for observed findings | |||
---|---|---|---|
1 | 2 | 3 | |
Encephalopathy grade* | 0 | 1 or 2 | 3 or 4† |
Ascites‡ | Absent | Slight | Moderate |
Serum bilirubin (µmol l−1) | <34.2 | 34.2–51.3 | >51.3 |
Serum albumin (g l−1) | >35 | 28–35 | <28 |
Prothrombin time (s prolonged) | <4 | 4–6 | >6 |
Grade 0: normal consciousness, personality, neurological examination, electroencephalogram. Grade 1: restless, sleep disturbed, irritable/agitated, tremor, impaired handwriting, 5 cps waves. Grade 2: lethargic, time-disoriented, inappropriate, asterixis, ataxia, slow triphasic waves. Grade 3: somnolent, stuporous, place-disoriented, hyperactive reflexes, rigidity, slower waves. Grade 4: unrousable coma, no personality/behaviour, decerebrate, slow 2–3 cps delta activity.
Patients with encephalopathy grade 3 and 4 were excluded from the study.
Patients with advanced ascites were excluded from the study.