Table 2.
(A) Genes that were found differentially expressed with highest occurrence in both experimental groups, (B) group 1 (oxidative stress), (C) group 2 (cellular aging)
| Symbol | Description | Unigene | GenBank | EG1 up | EG1 down | EG2 up | EG2 down | EG1 + EG2DE |
|---|---|---|---|---|---|---|---|---|
| (A) | ||||||||
| KIAA0101 | KIAA0101/PAF | Hs.81892 | NM_014736 | 7 | 7 | 6 | 7 | 27 |
| APOBEC3G | Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | Hs.660143 | NM_021822 | 0 | 10 | 8 | 8 | 26 |
| MEST | Mesoderm-specific transcript homolog (mouse) | Hs.270978 | NM_002402 | 4 | 5 | 8 | 8 | 25 |
| RRM2 | Ribonucleotide reductase M2 polypeptide | Hs.226390 | BE966236 | 7 | 5 | 4 | 9 | 25 |
| SYDE2 | Synapse defective 1, Rho GTPase, homolog 2 (C. elegans) | Hs.718601 | N90719 | 7 | 5 | 5 | 8 | 25 |
| TXNIP | Thioredoxin interacting protein | Hs.715525 | AA812232 | 2 | 9 | 7 | 7 | 25 |
| BHLHB2 | Basic helix-loop-helix domain containing, class B, 2 | Hs.719093 | NM_003670 | 5 | 6 | 10 | 3 | 24 |
| BICD1 | Bicaudal D homolog 1 (Drosophila) | Hs.505202 | BC010091 | 10 | 3 | 7 | 4 | 24 |
| CYP51A1 | Cytochrome P450, family 51, subfamily A, polypeptide 1 | Hs.417077 | U40053 | 10 | 1 | 10 | 3 | 24 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | Hs.397729 | NM_002130 | 9 | 3 | 9 | 3 | 24 |
| SKP2 | S-phase kinase-associated protein 2 (p45) | Hs.23348 | BC001441 | 5 | 9 | 3 | 7 | 24 |
| SLC1A4 | Solute carrier family 1 (neutral amino acid transporter), member 4 | Hs.654352 | W72527 | 6 | 1 | 11 | 6 | 24 |
| TCF8 | Transcription factor 8 (represses interleukin 2 expression) | Hs.282113 | NM_030751 | 6 | 6 | 6 | 6 | 24 |
| C20orf129 | Chromosome 20 open reading frame 129 | Hs.472716 | BC001068 | 11 | 1 | 7 | 4 | 23 |
| CD302 | CD302 antigen | Hs.130014 | NM_014880 | 7 | 4 | 6 | 6 | 23 |
| IFI44L | Interferon-induced protein 44-like | Hs.389724 | NM_006820 | 3 | 7 | 8 | 5 | 23 |
| PDGFD | Platelet derived growth factor D | Hs.352298 | NM_025208 | 5 | 4 | 6 | 8 | 23 |
| RUNX1 | Runt-related transcription factor 1 (acute myeloid leukemia 1) | Hs.675708 | BU789637 | 2 | 9 | 9 | 3 | 23 |
| TCEA3 | Transcription elongation factor A (SII), 3 | Hs.446354 | AI675780 | 2 | 8 | 4 | 9 | 23 |
| TSPAN2 | Tetraspanin 2 | Hs.310458 | AI743596 | 4 | 6 | 7 | 6 | 23 |
| Symbol | Description | Unigene | GenBank | EG1 up | EG1 down | EG1 DE |
|---|---|---|---|---|---|---|
| (B) | ||||||
| KIAA0101 | KIAA0101/PAF | Hs.81892 | NM_014736 | 7 | 7 | 14 |
| RRM2 | Ribonucleotide reductase M2 polypeptide | Hs.226390 | BC001886 | 8 | 6 | 14 |
| SKP2 | S-phase kinase-associated protein 2 (p45) | Hs.23348 | BC001441 | 5 | 9 | 14 |
| TRPV2 | Transient receptor potential cation channel, subfamily V, member 2 | Hs.279746 | NM_015930 | 4 | 10 | 14 |
| BICD1 | Bicaudal D homolog 1 (Drosophila) | Hs.505202 | BC010091 | 10 | 3 | 13 |
| EIF4A2 | Eukaryotic translation initiation factor 4A, isoform 2 | Hs.518475 | AI332397 | 10 | 3 | 13 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | Hs.406515 | NM_000903 | 9 | 4 | 13 |
| C20orf129 | Chromosome 20 open reading frame 129 | Hs.472716 | BC001068 | 11 | 1 | 12 |
| CASP1 | Caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | Hs.2490 | U13699 | 2 | 10 | 12 |
| CCNB2 | Cyclin B2 | Hs.194698 | NM_004701 | 5 | 7 | 12 |
| CIRBP | Cold-inducible RNA-binding protein | Hs.634522 | AL565767 | 8 | 4 | 12 |
| CKAP2 | Cytoskeleton-associated protein 2 | Hs.444028 | NM_018204 | 11 | 1 | 12 |
| CYBA | Cytochrome b-245, alpha polypeptide | Hs.513803 | NM_000101 | 3 | 9 | 12 |
| DAAM1 | Disheveled-associated activator of morphogenesis 1 | Hs.19156 | AA890373 | 8 | 4 | 12 |
| EGR1 | Early growth response 1 | Hs.326035 | NM_001964 | 6 | 6 | 12 |
| EIF5A | Eukaryotic translation initiation factor 5A | Hs.534314 | NM_001970 | 11 | 1 | 12 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | Hs.658370 | AW612461 | 7 | 5 | 12 |
| FBXO9 | F-box protein 9 | Hs.216653 | AK095307 | 8 | 4 | 12 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | Hs.397729 | NM_002130 | 9 | 3 | 12 |
| IGFBP3 | Insulin-like growth factor binding protein 3 | Hs.450230 | BF340228 | 4 | 8 | 12 |
| Symbol | Description | Unigene | GenBank | EG2 up | EG2 down | EG2 DE |
|---|---|---|---|---|---|---|
| (C) | ||||||
| SLC1A4 | Solute carrier family 1 (neutral amino acid transporter), member 4 | Hs.654352 | BF340083 | 11 | 7 | 18 |
| ARRB1 | Arrestin, beta 1 | Hs.503284 | BE207758 | 8 | 9 | 17 |
| APOBEC3G | Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | Hs.660143 | NM_021822 | 8 | 8 | 16 |
| MEST | Mesoderm-specific transcript homolog (mouse) | Hs.270978 | NM_002402 | 8 | 8 | 16 |
| CTSC | Cathepsin C | Hs.128065 | AI246687 | 10 | 5 | 15 |
| METTL7A | Methyltransferase like 7A | Hs.716437 | NM_014033 | 10 | 5 | 15 |
| GLIPR1 | GLI pathogenesis-related 1 (glioma) | Hs.205558 | AV682252 | 7 | 8 | 15 |
| RAB27B | RAB27B, member RAS oncogene family | Hs.25318 | BF438386 | 11 | 4 | 15 |
| TRIB3 | Tribbles homolog 3 (Drosophila) | Hs.516826 | NM_021158 | 10 | 5 | 15 |
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | Hs.159472 | AK025877 | 9 | 5 | 14 |
| EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1 | Hs.411641 | AB044548 | 8 | 6 | 14 |
| ETV1 | ets variant gene 1 | Hs.22634 | BE881590 | 9 | 5 | 14 |
| IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | Hs.714337 | AI075407 | 7 | 7 | 14 |
| KLF9 | Kruppel-like factor 9 | Hs.150557 | AI690205 | 3 | 11 | 14 |
| MCC | Mutated in colorectal cancers | Hs.593171 | BE967311 | 3 | 11 | 14 |
| PDGFD | Platelet derived growth factor D | Hs.352298 | NM_025208 | 6 | 8 | 14 |
| PHGDH | Phosphoglycerate dehydrogenase | Hs.487296 | NM_006623 | 4 | 10 | 14 |
| PHLDA1 | Pleckstrin homology-like domain, family A, member 1 | Hs.602085 | AK026181 | 10 | 4 | 14 |
| PTGS2 | Prostaglandin-endoperoxide synthase 2 | Hs.196384 | NM_000963 | 8 | 6 | 14 |
| RAB1A | RAB1A, member RAS oncogene family | Hs.709257 | BG530481 | 4 | 10 | 14 |