Table 3.
Geometric mean and 95% confidence intervals for total nevus counts by phenotype and 2-y sunburn history and site-specific nevus counts by site-specific sunburn history in children ages 7 to 8 y, Colorado (n =743)
| Geometric mean total nevus counts (95% confidence interval) | P* | |
|---|---|---|
| Sex | ||
| Female | 24.1 (22.6–25.7) | 0.01 |
| Male | 27.1 (25.5–28.9) | |
| Base skin color (tertiles of L-dimension)† | ||
| First (darkest) | 22.0 (20.4–23.8) | <0.0001 |
| Second (intermediate) | 27.2 (25.3–29.2) | |
| Third (lightest) | 27.7 (25.5–30.1) | |
| Hair color | ||
| Red | 14.5 (11.0–18.9) | <0.0001 |
| Blond | 27.3 (24.8–30.0) | |
| Light brown | 27.5 (25.5–29.7) | |
| Medium brown to black | 25.1 (23.4–26.8) | |
| Eye color | ||
| Blue/green | 27.8 (26.0–29.6) | <0.0001 |
| Brown | 21.7 (20.0–23.5) | |
| Hazel | 26.6 (24.2–29.3) | |
| Freckling on the face‡ | ||
| None | 21.3 (19.7–22.9) | <0.0001 |
| Some | 26.6 (24.9–28.4) | |
| Moderate | 29.9 (26.8–33.3) | |
| Heavy | 30.3 (24.2–37.8) | |
| Propensity to burn vs tan | ||
| Painful burn/no tan | 25.4 (20.9–30.7) | <0.0001 |
| Painful burn/light tan | 26.3 (24.0–28.7) | |
| Slight burn/little tan | 27.4 (25.7–29.1) | |
| No burn/good tan | 21.1 (19.1–23.4) | |
| Degree of tan (tertiles of b-dimension)x | ||
| First (least tan) | 22.1 (20.4–23.9) | <0.0001 |
| Second (intermediate) | 26.3 (24.3–28.4) | |
| Third (most tan) | 28.6 (26.5–30.9) | |
| No. sunburns | ||
| None | 21.6 (19.8–23.5) | <0.0001 |
| 1 | 25.9 (23.8–28.2) | |
| 2 | 27.6 (25.1–30.2) | |
| 3 | 28.7 (25.2–32.7) | |
| 4 | 31.5 (25.8–38.4) | |
| 5+ | 27.8 (22.7–33.9) | |
| Intervention status | ||
| Intervention | 25.7 (24.3–27.1) | 0.73 |
| Control | 25.3 (23.4–27.3) | |
| Site-specific geometric mean nevus counts (95% confidence interval) | P* | |
| No. sunburns on the face | ||
| None | 4.4 (4.0–4.8) | 0.37 |
| 1 | 4.8 (4.3–5.5) | |
| 2 | 3.9 (3.2–4.7) | |
| 3 | 4.1 (3.3–5.0) | |
| 4+ | 4.7 (3.5–6.2) | |
| No. sunburns on the back | ||
| None | 2.9 (2.7–3.2) | 0.02 |
| 1 | 3.5 (2.9–4.1) | |
| 2 | 3.8 (2.7–5.2) | |
| 3+ | 4.5 (3.0–6.6) | |
| No. sunburns on the arms | ||
| None | 7.0 (6.5–7.5) | 0.49 |
| 1 | 7.7 (6.3–9.5) | |
| 2+ | 7.9 (6.2–10.0) | |
| No. sunburns on the legs | ||
| None | 5.6 (5.2–6.0) | 0.23 |
| 1+ | 6.9 (5.0–9.4) | |
NOTE: Two-year sunburn history reported at ages 4 to 5 and 5 to 6 y for the previous 12 mo.
*
Using natural log-transformed nevus counts by one-way ANOVA or t test, as appropriate.
†
Measured by colorimeter, with L-dimension on the medial upper arm.
‡
By standardized chart.
§
Measured by colorimeter, as the difference in b-dimension between medial upper arm and lateral forearm.