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Histologic characteristics of the surgical site associated with the PBS group, siRNA group, and MMC group on day 60 after surgery. Treatment with IKKβ-siRNA (B) showed a marked reduction in subconjunctival scar tissue compared with the PBS group (A). The conjunctival epithelium appeared healthy, and the subepithelial connective tissue was loosely arranged, with moderate subconjunctival cavities, while the MMC treated eyes (C) exhibited marked acellularity and large bleb cavities.
