Fig. 2.

Conservation of AES protein sequence across species. Indicates percent homology of the Q domain, GP domain or entire AES protein for the indicated species relative to human AES. GRG5 is equivalent to mouse AES. Xenopus (x), Zebrafish (z), Rat (r). Percent homology was calculated using global alignment with BLOSUM 62 scoring matrix. Amino acid sequence for the identified proteins are based upon the following NCBI accession numbers: AES (NP_001121.2), GRG5 (NP_034477.1), rAES (NP_062093.1), xAES (NP_001083532.1), zAES (NP_956717.1).