Table 1.
Clinical Characteristics of TAAD Study Groups
|
Sporadic TAAD |
p Value | FTAAD (88)c | ||
|---|---|---|---|---|
| BCM (418) | UTHSCH (387) | |||
| Female | 36% | 35% | NS | 26% |
| Age | 63 (12) | 63 (12) | NS | 45 (14) |
| BMI | 27.8 (5.2) | 28.0 (6.1) | NS | 27.5 (5.5) |
| Smoking | 62% | 60% | NS | NA |
| Hypertension | 67% | 85% | <0.01 | NA |
| Diabetes | 5% | 7% | NS | 6% |
| Maximum aortic diametera | 5.9 (1.2) | 5.6 (1.0) | NS | 5.5 (1.8) |
| Bicuspid aortic valve | 15% | 23% | <0.01 | 15% |
| Dissectionb | 47% | 49% | NS | 44% |
| Stanford type A | 33% | 26% | 0.04 | 36% |
| Stanford type B | 15% | 23% | <0.01 | 8% |
| Aortic rupture | 2% | 4% | NS | 3% |
| Underwent aortic repair | 94% | 93% | NS | 57% |
| Involvement of ascending aorta | 89% | 83% | NS | 94% |
| Annuloaortic ectasia or root replacement | 24% | 33% | NS | 34% |
The following abbreviations are used: BCM, Baylor College of Medicine cohort; UTHSCH, University of Texas Health Science Center at Houston cohort; FTAAD, familial TAAD; p, probability value derived from Fisher's exact test; BMI, body mass index (kg/m2); NS, not significant. Categorical variables are shown as percentages, and continuous variables are shown as mean (standard deviation).
Aortic diameters were available for 397 BCM patients and 234 UTHSCH patients.
Four patients had both Stanford type A and type B dissections.
With the exception of age, gender, and aortic diagnosis (dissection, Stanford class, aortic rupture, repair, involvement of ascending aorta), values were calculated from 68 available records.