Fig. 4.

Comparison of histology between fundus and corpus in greater curvature of human stomach. In HE staining, the whole layer of fundus (Aa) and corpus (Ba) are shown. It is striking to find that fundus has prominent structure of oblique muscle, unlike corpus. c-Kit positive ICC is observed in every layer of human gastric fundus (Ab~Ag) and corpus (Bb~Bf) of greater curvature. Interestingly, almost all kinds of ICC are found in oblique muscle layer, however, ICCs of circular and longitudinal muscle are ICC-SEP. In panel (Bf and Bf inset), it is evident that ICC of longitudinal muscle has lots of processes and ramifications. Arrow: processes or ramification, arrow head: central cell body, double arrow head: ICC in septa (ICC-SEP).