Fig. 5.

Effect of corticosteroids (CS) administered after 3 months of chronic OVA challenge on numbers of bFGF+ cells/bronchus. Corticosteroids or diluent were administered for 1 month to different groups of mice that had previously received 3 months of chronic OVA challenge. A non-OVA challenged group served as a control. Lung sections from the different groups of mice were processed to detect the number of bFGF+ cells/bronchus. Chronic OVA challenge induced a significant increase in the number of bFGF+ cells/bronchus (p < 0.0001), which was significantly reduced by corticosteroid therapy (p < 0.0001) (n = 16 mice/group).