Table 3.
Blood urea nitrogen and serum creatinine concentration in different groups of rats
| Group | Blood urea nitrogen (BUN) (mg/dl) |
Serum creatinine concentration (mg/dl) |
||||
|---|---|---|---|---|---|---|
| Day 0 | Day 4 | Day 14 | Day 0 | Day 4 | Day 14 | |
| Acetaminophen (APAP) (1 – 3 days) | 23.14 ± 1.85aABC | 38.49 ± 2.65aEF | 36.10 ± 2.57cE | 0.77 ± 0.03aAB | 1.42 ± 0.14aE | 1.09 ± 0.05bCD |
| APAP (1 – 3 days) + silymarin (4 – 14 days) | 18.24 ± 2.05aA | 38.62 ± 0.81aEF | 29.18 ± 0.77abcD | 0.70 ± 0.06aAB | 1.18 ± 0.10aD | 0.88 ± 0.08aABC |
| APAP (1 – 3 days) +Terminalia chebula (4 – 14 days) | 20.63 ± 2.97aAB | 40.50 ± 2.45aEF | 33.98 ± 0.73bcDE | 0.66 ± 0.04aA | 1.16 ± 0.06aD | 0.90 ± 0.07abBC |
| APAP (1 – 3 days) + silymarin +Terminalia chebula (4 – 14 days) | 20.88 ± 2.04aAB | 44.65 ± 2.66aF | 26.92 ± 1.87aBC | 0.77 ± 0.03aAB | 1.18 ± 0.06aD | 0.85 ± 0.02aAB |
Values are mean ± SE of six observations; Means with different alphabets as superscripts differ significantly (P<0.05) ANOVA; Capital alphabets (horizontal comparison), small alphabets (vertical comparison)