Table 2.

Cardiac functional parameters. Fractional shortening (FS) determined by echocardiography and cine magnetic resonance imaging (MRI), fractional area change (FAC) determined by cine magnetic resonance imaging. Values shown as mean percentage ± standard deviation before (preop), 24 h and 1 week after ischemia/reperfusion procedure for mice with no ischemia (sham), 30 min or 60 min of ischemia during procedure. Troponin T levels (ng/ml) are shown for each group. *Significant difference to sham-operated mice; ^†Significant difference to 60 min operated mice; all P < .05.

	0 min = sham	30 min	60 min
FS echo preop (%)	50.8 ± 3.7	50.5 ± 3.1	51.5 ± 3.6
FS MRI preop (%)	48.2 ± 5.1	47.5 ± 5.3	47.4 ± 3.6
FAC preop (%)	55.5 ± 5.4	55.7 ± 6.3	52.5 ± 2.7
FS echo 24 h (%)	51 ± 5.5†	41.1 ± 5.6*	40.7 ± 3.6*
FS MRI 24 h (%)	45.8 ± 8.6†	33.1 ± 9.7*	26.2 ± 4.6*
FAC 24 h (%)	55.3 ± 6.9†	42.8 ± 6.9*	38.6 ± 3.6*
FS echo 1 W (%)	55.3 ± 1.6†	43.2 ± 4.2∗,†	37.7 ± 5.9*
FS MRI 1 W (%)	50.7 ± 2.4†	39.1 ± 5.4∗,†	32.2 ± 10.2*
FAC 1 W (%)	59.6 ± 6.1†	46.4 ± 2.8∗,†	36.9 ± 8.8*
Troponin T (ng/ml)	0.1 ± 0.1	2.4 ± 0.7*	3.8 ± 2.0*