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. Author manuscript; available in PMC: 2010 Dec 6.
Published in final edited form as: J Mol Biol. 2009 Sep 19;394(3):496–505. doi: 10.1016/j.jmb.2009.09.035

Figure 3. Ca2+ binding stabilizes HC/RLC/ELC interactions in scallop structures.

Figure 3

(a) Shown is a vast hydrogen-bond and covalent bond network in the Ca2+-RD structure extending from the Ca2+ binding site to Lys149 on the RLC N-lobe. (b) Part of this network forms a meshwork that stabilizes the coordination of the Ca2+ ion, shown here schematically. Solid gray lines indicate main-chain interactions and wavy lines indicate side-chain interactions. (c) The same meshwork as b in the absence of Ca2+. Notice that when the Gly23 carbonyl rotates away from the Ca2+ binding site, four hydrogen bonds from this meshwork are abolished.