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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Biotechnol Prog. 2010 Jul–Aug;26(4):1014–1023. doi: 10.1002/btpr.395

Figure 6. Cell volume fractions at various RPM and a constant inlet velocity of 6.5 cm/s are shown.

Figure 6

Experimental cell volume fractions of 0.16 and 0.26 at 650 and 920 RPM were determined assuming a cell bed of uniform density and a volume calculated from still photographs. Simulation results along the reactor centerline indicate similar maximum cell volume fractions of 0.15 and 0.22 for RPMs of 650 and 920, respectively. The diffuse interface at the top of the cell bed in numerical results can be attributed to artificial diffusion, while a constant maximum cell volume fraction is not predicted in simulations due to the accumulation of cells along the right wall of the reactor.