Table 5.
Comparative analysis of intraoperative outcome and postoperative biochemical profile and outcome in the ‘livers that nobody wants’ (LNW) (n = 26) and control (n = 25) groups
| LNW group | Control group | P-value | |
|---|---|---|---|
| Intraoperative outcome | |||
| Extubation in the ORa, n (%) | 5 (19.2) | 7 (26.9) | 0.68 |
| Biochemical profileb | |||
| Peak total bilirubin, mg/ml, median (range) | 3.5 (0.9–14) | 6.1 (1.5–25) | 0.01 |
| Peak ALT, U/l, median (range) | 590 (163–4890) | 590 (163–4890) | 0.20 |
| Peak AST, U/l, median (range) | 533 (162–2870) | 895 (240–17600) | 0.19 |
| Peak AST > 1500 U/l, n (%) | 5 (19.2) | 6 (24) | 0.94 |
| Prothrombin time < 50%, n (%) | 13 (50) | 12 (48) | 1.00 |
| Primary delayed function, n (%) | 4 (15.3) | 4 (16) | 0.74 |
| Postoperative outcome | |||
| Primary non-function, n (%) | 1 (3.8) | 1 (4) | 0.48 |
| Renal failurec, n (%) | 2 (7.6) | 1 (4) | 0.97 |
| Major complications, n (%) | 4 (15.3) | 5 (20) | 0.94 |
| ICU stay, days, median (range) | 3 (1–12) | 2 (1–27) | 0.58 |
| Hospital stay, days, median (range) | 8 (5–33) | 8 (4–47) | 0.64 |
| 30-day mortality, n (%) | 1 (3.8) | 2 (8.0) | 0.97 |
| 1-year patient survival rate | 84% | 84% | 0.74 |
| 1-year graft survival rate | 84% | 80% | 0.94 |
Withdrawal of mechanical ventilation in the operating room
Peak serum transaminases and total bilirubin or lower prothrombin time within the first week after liver transplant
Requiring haemodialysis or haemofiltration
OR, operating room; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ICU, intensive care unit