Table 1. Expression of ARRDC3 in human breast tumors.
| ID | HER2 | ER | PR | Cancer type | Grade | ITGβ4 | ARRDC3 |
|---|---|---|---|---|---|---|---|
| 0630T | − | + | Weak | Lobular carcinoma | 1 | + | +++ |
| 0832T | − | + | − | Ductal carcinoma | 1 | + | +++ |
| 0885T | − | + | + | Ductal carcinoma | 1 | + | ++ |
| 0909T | − | + | Weak | Ductal carcinoma | 1 | − | +++ |
| 1334T | − | + | + | Lobular carcinoma | 1 | +++ | + |
| 1640T | − | + | − | Ductal carcinoma | 1 | ++ | ++ |
| 0199T | + | + | + | Ductal carcinoma | 2 | ++ | ++ |
| 0248T | − | + | + | Ductal carcinoma | 2 | +++ | + |
| 0327T | + | + | + | Ductal carcinoma | 2 | ++ | ++ |
| 0424T | − | + | + | Papillary carcinoma | 2 | − | + |
| 0448T | − | − | − | Ductal carcinoma | 2 | +++ | + |
| 0462T | − | + | − | Ductal carcinoma | 2 | ++ | ++ |
| 0480T | − | + | + | Ductal carcinoma | 2 | + | + |
| 0545T | + | + | − | Ductal carcinoma | 2 | ++ | ++ |
| 0576T | − | + | − | Ductal carcinoma | 2 | +++ | + |
| 0638T | − | + | − | Ductal carcinoma | 2 | + | ++ |
| 0837T | Weak/− | − | − | Ductal carcinoma | 2 | ++ | + |
| 0884T | − | + | − | Lobular carcinoma | 2 | ++ | + |
| 0934T | + | − | − | Ductal carcinoma in situ | 2 | +++ | + |
| 0960T | + | + | + | Ductal carcinoma | 2 | + | + |
| 1003T | − | + | + | Ductal carcinoma | 2 | − | ++ |
| 1099T | − | + | − | Ductal carcinoma | 2 | + | + |
| 1281T | − | + | + | Lobular carcinoma | 2 | ++ | − |
| 1376T | − | + | + | Lobular carcinoma | 2 | +++ | + |
| 1403T | + | + | + | Ductal carcinoma | 2 | ++ | ++ |
| 1404T | − | + | + | Lobular carcinoma | 2 | +++ | + |
| 1471L | − | + | + | Carcinoma | 2 | +++ | + |
| 1471T | − | + | + | Ductal carcinoma | 2 | +++ | + |
| 1502T | − | + | + | Ductal carcinoma | 2 | ++ | ++ |
| 1569T | − | + | + | Ductal carcinoma | 2 | + | +++ |
| 0237T | + | − | − | Ductal carcinoma | 3 | +++ | − |
| 0316T | + | − | + | Ductal carcinoma | 3 | +++ | + |
| 0442T | + | − | − | Ductal carcinoma | 3 | +++ | + |
| 0454T | − | + | + | Lobular carcinoma | 3 | +++ | ++ |
| 0471T | + | + | − | Lobular carcinoma | 3 | − | + |
| 0489T | − | + | + | Lobular carcinoma | 3 | + | − |
| 0577T | − | + | − | Lobular carcinoma | 3 | +++ | + |
| 0690T | − | − | − | Ductal carcinoma | 3 | − | + |
| 0738T | − | − | + | Ductal carcinoma | 3 | +++ | + |
| 0839T | − | − | − | Ductal carcinoma | 3 | − | − |
| 0902T | − | − | − | Ductal carcinoma | 3 | − | ++ |
| 0957T | − | − | − | Ductal carcinoma | 3 | +++ | + |
| 0959M | − | + | − | Carcinoma | 3 | − | + |
| 0959T | − | + | − | Ductal carcinoma | 3 | + | + |
| 1060T | − | + | − | Ductal carcinoma | 3 | + | + |
| 1097T | Weak | + | Weak | Ductal carcinoma | 3 | ++ | + |
| 1200T | − | − | − | Ductal carcinoma | 3 | +++ | − |
| 1342M | − | − | − | Ductal carcinoma | 3 | +++ | + |
| 1550T | − | + | + | Lobular carcinoma | 3 | +++ | + |
| 1623T | − | + | + | Ductal carcinoma | 3 | +++ | + |
| 1645T | NR | + | + | Lobular carcinoma | 3 | ++ | − |
| 1659T | − | + | − | Ductal carcinoma | 3 | +++ | + |
Abbreviations: −, indicates no detectable expression; +, is low expression; ++, is moderate expression; +++, is high expression; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; ITGβ4, integrin β4; NR, not reported; PR, progesterone receptor.
A table of the 52 human breast tumors analyzed for ARRDC3 and ITGβ4 expression using immunofluorescence. ID refers to the UMass Tissue Bank tumor number. HER2, ER and PR statuses, cancer type and grade are those determined at the time of diagnosis. All samples were processed at the same time using the same master-mix of primary and secondary antibodies. Images from each sample were taken all on the same day using the same exposure times for each channel. Expression levels were scored by a pathologist (SL) blinded to the sample information.