Table 3. Final monomer rmsd measurements after 100ns of dynamics.

Backbone rmsds are given as averages over all 48 protein monomers in each simulation cell; standard deviations in the rmsds obtained for all individual monomers provide error bars.

	Monomer RMSD (Å)
Water Model	FF99SB	FF03	CHARMM22	OPLS
SPC/E	0.61 ± 0.06	0.82 ± 0.14	0.85 ± 0.10	1.22 ± 0.18
TIP3P	0.59 ± 0.07	0.92 ± 0.11	0.91 ± 0.14	1.39 ± 0.22
TIP3P-Ew	0.57 ± 0.04	0.86 ± 0.15	0.82 ± 0.11	1.28 ± 0.28
TIP4P-2005	0.66 ± 0.11	0.86 ± 0.11	0.91 ± 0.10	1.17 ± 0.20