Table III. Biomarker Expression of the Entire Tissue Sample by Western or in the Basal Cell Layer by IHC.
Western* | ||||
Tumors | p-AKT | p-MTOR | p-S6 | p-4EBP1 |
+ | 32 | 18 | 17 | 10 |
- | 12 | 12 | 27 | 34 |
Total | 44 | 30 | 44 | 44 |
Junctional Zone | ||||
+ | 16 | 13 | 11 | 10 |
- | 1 | 3 | 8 | 9 |
Total | 17 | 16 | 19 | 19 |
Sensitivity Tumors | 72.7% | 60.0% | 38.6% | 22.7% |
Junctional Zone | 94.1% | 81.3% | 57.9% | 52.6% |
IHC | ||||
Tumors | p-MTOR | p-4EBP1 | ||
+ | 59 | 36 | ||
- | 13 | 36 | ||
Total | 72 | 72 | ||
Uvula | ||||
+ | 0 | 1 | ||
- | 22 | 21 | ||
Total | 22 | 22 | ||
Sensitivity | 81.9% | 50.0% | ||
Specificity | 100% | 95.5% |