Skip to main content
. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: J Am Chem Soc. 2010 Nov 10;132(47):16812–16817. doi: 10.1021/ja105429n

Figure 4.

Figure 4

Analogs of the reactive alanine-lysine motif identified during library screening were synthesized to verify the reactivity of this sequence. AKT was compared to LKT to confirm the importance of alanine as the first residue and AET was used to probe the role of a positive charge in the second position. At 0.1 mM PLP, the concentration of library screening, AKT showed a significantly higher yield than the other sequences. AKT also resulted in notably improved yields at higher concentrations of PLP.