TABLE 2.
Typical concentrations of AgSD and PROLI/NO that elicited optimum synergistic effect, the correlating fold decrease over the respective values required for bactericidal activity alone, and the fractional bactericidal concentration (FBC120) for each species. The dashed line demarks the transition from synergistic to indifferent.
| Species | AgSD | PROLI/NO | |||
|---|---|---|---|---|---|
| combination (g L−1) | fraction (%) | combination (g L−1) | fraction (%) | FBC120 | |
| MRSA | 0.400 | 12.5 | 2.25 | 6.25 | 0.23 |
| VREF | 0.500 | 12.5 | 3.75 | 6.25 | 0.31 |
| E. faecalis | 0.250 | 12.5 | 9.0 | 12.5 | 0.33 |
| S. aureus | 0.100 | 16.7 | 12.0 | 25 | 0.42 |
| E. coli (O157:H7) | 0.050 | 25 | 6.0 | 25 | 0.53 |
| P. mirabilis | 0.050 | 50 | 0.75 | 6.25 | 0.56 |
| P. aeruginosa | 0.005 | 25 | 2.0 | 25 | 0.63 |
| E. coli (JM109) | 0.0125 | 25 | 0.25 | 12.5 | 0.67 |
| S. epidermidis | 0.050 | 50 | 18.0 | 50 | 1.00 |