Table I.

Structures of the proteins that belong to the Class II cytokines family deposited in the PDB.

Protein	Biol. relev. aggregation	Species	Expression system	PDB code/Reference	Resolution/Remarks
IL-10	Dimer	Human	E. coli	1ILK/[66]	1.8 Å, room temp
IL-10	Dimer	Human	E. coli	2ILK/[67]	1.6 Å, 100 K.
IL-10	Dimer	Human	E. coli	1INR/[94]	2.0 Å
IL-10	Dimer	Human	E. coli	2H24/[88]	2.0 Å
Epstein-Barr IL-10	Dimer	EBV	E. coli	1VLK/[95]	1.9 Å
IL-19	Monomer	Human	DES2	1N1F/[64]	1.95 Å
IL-22	Monomer	Human	E. coli	1MR4/[65]	2.0 Å
IL-22	Monomer	Human	DES2	1YKB/[96]	2.6 Å
IFN-λ3	Monomer	Human	E.Coli	3HHC[74]	2.8 Å
IL-10/sIL-10R1	Tetramer	Human	E. coli, DES2	1J7V/[78]	2.9 Å
IL-10/sIL-10R1mut	Tetramer	Human	E. coli, DES2	1Y6K/not publ.	2.52 Å
EBV IL-10/sIL-10R1, and mut.	Tetramer	EBV	E. coli, DES2	1Y6M,1Y6N/[84]	2.8 Å, 2.7 Å
CMV IL-10/sIL-10R1	Tetramer	CMV	E. coli, DES2	1LQS/[83]	2.7 Å
IL-10 monomer/9D7 Fab	Trimer	Human Rat	E. coli	1LK3/[97]	1.91 Å
IL-22/IL-22R1	Dimer	Human	E. coli	3DLQ[79]	1.9 Å
IL-22/IL-22R1	Dimer	Human	DES2	3DGC[80]	2.5 Å
IL-22/ILBP	Dimer	Human	E. coli	3G9V[81]	2.76 Å

¹Chinese hamster ovary cells;

²Drosophila expression system, Sf9 cells.