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. Author manuscript; available in PMC: 2011 Dec 6.
Published in final edited form as: Mol Pharm. 2010 Oct 29;7(6):2006–2019. doi: 10.1021/mp100280b

Figure 8.

Figure 8

Change in fluorescence intensity in MCF-7 spheroid's core (0.25r), intermediate layers (0.50r and 0.75r), and surface (1.00r) upon incubation with 50 μl of Optison microspheres and (A) 20 nm CdSe particles with non-functionalized surface (neutral) or (B) 20 nm cationic particles with primary amine surface groups upon exposure to pulsed US at 10% DC. All results are the average of 15 samples ± the standard error of the mean. The * indicates p < 0.05, ** p < 0.01, and *** p < 0.005 when comparing the test and control groups.