Table 2.

Results from bivariate analyses of traits measured in different dietary environments; given are heritabilities (h²), genetic correlations (ρ_G), and genetic variances (σ²_G) for each trait in the model and the P-values associated with the tests for complete pleiotropy and equality of genetic variance.^*

Increase Dietary Fat:			Test for complete pleiotropy:				Test for equal σ²_G:
Basal	HFLC		h²			P-value: ρ_G=1	σ²_G		P-value: σ²_G(1) = σ²_G(2)

Trait1	Trait2	N	Trait1	Trait2	ρ_G		Trait1	Trait2

Hmed	Hmed	715	0.532	0.562	0.977	5.8E-02	0.443	0.458	7.8E-01
HDLC	HDLC	715	0.696	0.668	0.976	1.4E-02	0.566	0.533	5.7E-01
ApoA1	ApoA1	716	0.556	0.438	0.984	2.6E-01	0.510	0.407	1.3E-01
Bmed	Bmed	715	0.293	0.380	0.998	9.5E-01	0.275	0.352	1.6E-01
LDLC	LDLC	715	0.640	0.630	0.965	5.2E-02	0.509	0.501	9.0E-01
ApoB	ApoB	716	0.425	0.466	1.000	1.0E+00	0.349	0.377	4.6E-01

Increase Dietary Cholesterol:			Test for complete pleiotropy:				Test for equal σ²_G:
HFLC	HFHC		h²			P-value: ρ_G=1	σ²_G		P-value: σ²_G(2) = σ²_G(3)

Trait2	Trait3	N	Trait2	Trait3	ρ_G		Trait2	Trait3

Hmed	Hmed	715	0.567	0.570	0.982	9.2E-02	0.463	0.466	9.6E-01
HDLC	HDLC	715	0.694	0.609	0.926	1.9E-05	0.566	0.521	5.7E-01
ApoA1	ApoA1	716	0.470	0.364	0.849	8.5E-04	0.442	0.357	4.0E-01
Bmed	Bmed	715	0.300	0.548	0.970	2.1E-01	0.272	0.458	1.3E-02
LDLC	LDLC	715	0.619	0.691	0.874	1.6E-06	0.486	0.496	8.8E-01
ApoB	ApoB	716	0.450	0.622	0.842	1.0E-07	0.364	0.467	1.4E-01

σ²_G, h² (σ²_G/σ²_P), and ρ_G were estimated using routines in SOLAR; P-values in bold were significant at the P<0.05 level