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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Atherosclerosis. 2010 Sep 28;213(2):499–504. doi: 10.1016/j.atherosclerosis.2010.08.079

Table 4.

Results of quadrivariate genetic analyses of the same pair of traits in two dietary environments to test effects of increasing dietary fat and cholesterol; given are N, ρG±SE for the trait pairs compared across diet, and P-values for the tests of the hypothesis that the two within-diet correlations are the same.

Increase Dietary Fat:
Basal
 HFLC
 ρG
 P-value:
Trait1 Trait2 Trait3 Trait4 N T1/T2 T3/T4 t-test LRT*
Hmed HDLC Hmed HDLC 715 0.803±0.035 0.883±0.035 1.00E-01 -
Hmed ApoA1 Hmed ApoA1 715 0.644±0.094 0.708±0.091 6.20E-01 4.27E-01
HDLC ApoA1 HDLC ApoA1 715 0.903±0.035 0.925±0.035 6.61E-01 5.31E-01
Bmed LDLC Bmed LDLC 713 0.303±0.123 0.314±0.118 9.47E-01 9.18E-01
Bmed ApoB Bmed ApoB 712 0.076±0.138 0.063±0.133 9.44E-01 8.93E-01
LDLC ApoB LDLC ApoB 714 0.922±0.039 0.900±0.034 6.82E-01 6.07E-01
Increase Dietary Cholesterol:
HFLC
 HFHC
 ρG
 P-value:
Trait1 Trait2 Trait3 Trait4 N T1/T2 T3/T4 t-test LRT*
Hmed HDLC Hmed HDLC 715 0.851±0.046 0.762±0.070 2.71E-01 7.95E-02
Hmed ApoA1 Hmed ApoA1 715 0.717±0.092 0.423±0.094 2.61E-02 8.26E-03
HDLC ApoA1 HDLC ApoA1 715 0.922±0.094 0.877±0.091 7.27E-01 -
Bmed LDLC Bmed LDLC 715 0.191±0.130 0.608±0.073 5.40E-03 4.20E-05
Bmed ApoB Bmed ApoB 715 0.004±0.133 0.386±0.099 2.14E-02 1.34E-03
LDLC ApoB LDLC ApoB 715 0.904±0.035 0.924±0.021 6.29E-01 5.46E-01
*

LRT, loge likelihood ratio test; P-values in bold were significant at the 0.05 level and dashes indicate models that failed to converge.