. Author manuscript; available in PMC: 2011 Dec 6.

Published in final edited form as: Mol Pharm. 2010 Nov 1;7(6):2240–2254. doi: 10.1021/mp100233v

Table 2.

Conjugates that were non-substrate for ASBT. R₁ and R₂ refer to substituents on the same general structure in Table 1.

Compound	R₂	Charge	Pp × 10⁶ (cm/s)
28	H	−2 (Dianion)	0.216±0.012
29	H	−2 (Dianion)	0.104±0.005
30	CH₂C₆H₅	+1 (Cation)	4.71±0.09
31	H	zwitterion	0.204±0.023
32	H	zwitterion	0.336±0.017