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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Ophthalmology. 2010 Sep 15;117(12):2322–2328.e1. doi: 10.1016/j.ophtha.2010.03.042

Table 4.

Effect size statistic calculated for AS-20 and VFQ-25 in adults undergoing strabismus surgery.

Effect size: Effect size (Mean change / Pre-op standard deviation)
Diplopia (n=80) No diplopia (n=26)
AS-20 questionnaire Success (n=46) Partial success (n=27) Failure (n=7) Success (n=19) Partial success (n=5) Failure (n=2)
AS-20 composite score 1.27 (25.3/19.8) 0.88 (17.5/19.9) 0.47 (8.0/17.1) 1.43 (21.8/15.3) 0.99 (12.9/13.1) −0.18 (−3.1/17.7)
Psychosocial subscale 0.67 (17.3/25.5) 0.48 (11.3/23.6) 0.20 (5.0/25.2) 1.44 (30.0/20.9) 0.59 (16.4/27.7) 0.28 (2.5/8.8)
Function subscale 1.56 (33.3/21.3) 1.02 (21.0/20.6) 0.64 (11.1/17.2 0.70 (13.7/19.6) 0.61 (9.5/15.5) −0.20 (−8.8/44.2)
VFQ-25 questionnaire
VFQ-25 composite score 1.14 (20.5/18.0) 0.69 (11.9/17.2) 0.54 (8.4/15.7) 0.57 (6.6/11.6) 0.41 (1.7/4.1) −3.33 (−15.4/4.6)
General health 0.09 (2.2/23.2) −0.04 (−0.9/26.3) 0.00 (0.0/23.8) 0.22 (5.3/24.0) 0.37 (5.0/13.7) 0.35 (25.0/70.7)
General vision 1.13 (23.5/20.8) 0.69 (12.6/18.3) 0.53 (11.4/21.4) 0.48 (7.4/15.4) NA (12.0/0.0) 0.0 (0.0/14.1)
Ocular pain 0.68 (15.5/22.7) 0.28 (6.5/23.2) 0.11 (1.8/16.8) 0.22 (5.3/23.8) 0.0 (0.0/14.3) −2.12 (−18.8/8.8)
Near activities 1.10 (23.7/21.5) 0.61 (15.7/25.8) 0.57 (10.1/17.6) 0.36 (5.3/14.5) 0.0 (0.0/4.2) −0.71 (−16.7/23.6)
Distance activities 1.06 (21.6/20.4) 0.51 (12.8/25.3) 0.23 (4.8/20.8) 0.53 (8.8/16.4) −0.67 (−5.0/7.5) −0.24 (−4.2/17.7)
Vision specific social functioning 0.72 (14.9/20.7) 0.41 (7.9/19.2) 0.77 (10.7/13.9) 0.66 (10.5/15.9) NA (0.0/0.0) NA (−25.0/0.0)
Vision specific mental health 1.18 (34.0/28.7) 0.96 (22.2/23.2) 0.04 (0.9/20.5) 0.76 (14.5/19.1) −0.80 (−5.0/6.3) −0.80 (−17.7/22.1)
Vision specific role difficulties 0.97 (29.9/30.9) 0.58 (15.9/27.2) 0.56 (16.1/28.6) 0.32 (5.9/18.3) 0.45 (5.0/11.2) NA (−37.5/0.0)
Vision specific dependency 0.64 (17.4/27.0) 0.60 (13.3/21.9) 0.18 (4.2/22.6) 0.29 (5.3/18.4) 0.45 (1.7/3.7) NA (−16.7/0.0)
Driving 0.62 (18.7/30.2) 0.46 (10.3/22.3) 0.31 (6.9/22.6) 0.18 (3.9/22.0) −0.15 (−1.7/10.9) NA (−8.3/0.0)
Color vision 0.31 (4.9/16.0) 0.08 (1.0/11.8) 0.80 (10.7/13.4) 0.23 (1.3/5.7) NA (0.0/0.0) NA (−12.5/0.0)
Peripheral vision 0.80 (21.2/26.6) 0.46 (12.0/26.3) 0.62 (21.4/34.5) 0.18 (3.9/22.1) 0.45 (10.0/22.4) −0.71 (−12.5/17.7)

Effect size is calculated by dividing mean pre- to post-operative change by pre-operative standard deviation. A higher effect size statistic indicates a more responsive measure. Results are shown for patients with and without diplopia, by success, partial success and failure. NA = not applicable / unable to calculate. AS-20 = Adult Strabismus-20; VFQ-25 = National Eye Institute Visual Function Questionnaire-25