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. Author manuscript; available in PMC: 2011 Dec 6.
Published in final edited form as: Mol Pharm. 2010 Nov 11;7(6):2334–2348. doi: 10.1021/mp100308n

Figure 5.

Figure 5

Morphological analysis of domains of lipids obtained from resistant and sensitive cells. The LB films were transferred at SP 30 mN/m and analyzed using an AFM. Section profiles of the height images show large and more heterogeneous domains for resistant cell membrane lipids than for sensitive cell membrane lipids. FFT images of the corresponding height images revealed that resistant cell membrane lipids form more condensed film than sensitive cell membrane lipids. The 3D height image clearly shows a greater degree of lateral heterogeneity in the LB films of resistant cell membrane lipids than sensitive cell membrane lipids, thus confirming the section profile analysis.