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. Author manuscript; available in PMC: 2010 Dec 6.
Published in final edited form as: Expert Rev Proteomics. 2008 Oct;5(5):721–730. doi: 10.1586/14789450.5.5.721

Figure 3. Cleavable and ‘’click” chemistry linkers.

Figure 3

A: Reduction cleavage of disulfide and diazo cleavable linkers.

B: Mechanism of ‘’click” chemistry. Cycloaddition of an azide and alkyne functional group is used for the tag attachment after protein labeling.