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The expression of Toll-like receptor 3 (TLR3), vascular endothelial growth factor (VEGF), interleukin (IL)-8 in rheumatoid arthritis (RA) and osteoarthritis (OA) synovium. TLR3, VEGF and IL-8 expression increases in the RA synovium than that of OA. The expression of TLR3, VEGF and IL-8 in RA and OA synovium was detected using immunohistochemical staining by using specific Abs. All tissues were counterstained with hematoxylin (× 400).
