Skip to main content
. 2010 Dec 7;16(45):5701–5709. doi: 10.3748/wjg.v16.i45.5701

Table 2.

Intestinal morphology following cold ischemic storage

Time (h) Group Grade Median Significance Event
2 D1 0, 2, 6, 7 4 Denuded villi
D2 3, 4, 6, 6 5 Loss of villi
D3 1, 2, 2, 3 2 D3, D4, D5 vs D1, D2, P = 0.06 Moderate clefting
D4 1, 2, 3, 5 2.5 Moderate-extensive clefting
D5 1, 2, 3, 4 2.5 Moderate-extensive clefting
12 D1 0, 6, 7, 8 6.5 Injury to crypts and submucosa
D2 2, 6, 7, 7 6.5 Injury to crypts and submucosa
D3 3, 7, 8, 8 7.5 Injury to crypts, submucosa and muscularis
D4 3, 6, 8, 8 7 Injury to crypts and submucosa
D5 0, 4, 4, 5 4 D5 vs D1-D4, P < 0.05 Clefting and denuded villi

A modified Park’s classification for intestinal injury was used to assess mucosal morphology as follows: Grade 0: Normal mucosa; Grade 1: Subepithelial space at villus tip; Grade 2: Moderate subepithelial space; Grade 3: Epithelial lifting along villus sides; Grade 4: Denuded villi; Grade 5: Loss of villus tissue; Grade 6: Crypt layer injury; Grade 7: Transmucosal injury; Grade 8: Transmural injury.