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. Author manuscript; available in PMC: 2010 Dec 6.
Published in final edited form as: J Immunol. 2008 Oct 15;181(8):5738–5747. doi: 10.4049/jimmunol.181.8.5738

FIGURE 2.

FIGURE 2

Passive transfer of col(V) immune serum or purified IgG, or adoptive transfer of purified B cells from to isograft recipients induces rejection-like pathology in isograft lungs. Col(V) or HEL immune serum or purified IgG or B cells from col(V)-immunized rats were isolated and transferred to lung isograft recipients and lung tissues collected posttransfer as described in Materials and Methods. A, Passive transfer of col(V) immune serum. B, Passive transfer of IgG purified from col(V) immune serum. C, Adoptive transfer of B cells from col(V) immunized rats. D, Passive transfer of HEL immune serum. E, Passive transfer of IgG purified from HEL immune serum. No pathologic lesions are observed in isograft lungs of rats that received HEL immune sera or IgG purified from HEL-immunized rats (A and B, respectively). Arrows indicate perivascular and peribronchiolar infiltrates (A–C). Data are representative of n = 4–6 rats in each group. Magnification of H&E stained lung sections is ×20.