Table 1.

Possible targets of NSAIDs.

Molecular target	Functional target	References
PPAR	Inflammation (via NFkB)	Pascual et al. (2005)
	Oxidative stress	Nunomura et al. (2001), Kang et al. (2005)
	Apoptosis	Fuenzalida et al. (2007)
	Cerebrovascular protection	Nicolakakis et al. (2008)
	BACE	Sastre et al. (2006)
Rho-GTPases	Axon growth	Fu et al. (2007)
	Tau phosphorylation	Sayas et al. (1999)
	Astrocyte motility	Lichtenstein et al. (2010)
COX	Microglia modulation	Choi et al. (2009)
ApoE	Astrocyte dysfunction	Zhong et al. (2009)
γ-Secretase	Reduction of Ab42	Weggen et al. (2003)