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. Author manuscript; available in PMC: 2010 Dec 6.
Published in final edited form as: Nano Today. 2010 Feb;5(1):28–47. doi: 10.1016/j.nantod.2009.12.001

Figure 3.

Figure 3

Spatiotemporal drug control. (A) Picture from 2 min movie showing successive perfusion with Trypan blue dye on live cell, and subsequent methanol and Trypan after cell death. (B) Picture showing the ability to change the stream in contact with a cell by changing inlet flow rate. This type of medium switching can be done in 130 ms [37]. (C) Schematic of PARTCELL principle [36]. Using laminar flow properties one is able to partially treat a cell. Picture shows treatment of a portion of a single cell with Latrunculin A and blue dye. (D) Picture showing hydrodynamic focusing. Flows B (green) arriving from both sides of flow A (red) focused and maintained flow in a fine stream configuration [40].