FIGURE 6.

Differential effects of ROS on Cav-1 expression, cell migration, and invasion. Western blot analysis is shown of Cav-1 expression in H460 cells treated with the indicated concentrations of DMNQ and MnTBAP (A), H₂O₂ and CAT (B), and FeSO₄ and NaFM (C) for 24 h. Cell migration was determined 24 h after the treatment with DMNQ and MnTBAP(D), H₂O₂ and CAT (E), and FeSO₄ and NaFM (F). Cell invasion was determined 24 h after the treatment with DMNQ (5 μm), H₂O₂ (100 μm), and FeSO₄ (50 μm) (G). Data are the mean ± S.D. (n = 3). *, p < 0.05 versus nontreated control.