Effects of ROS modulators on cell migration and invasion in Cav-1-overexpressing H460 cells and G361 melanoma cells. A and B, migration and invasion of Cav-1 stably transfected H460 cells determined at 24 h after the treatment with DMNQ (5 μm), H2O2 (100 μm), and FeSO4 (50 μm). Experiments were performed using wound assay and Transwell assay, respectively. C and D, experiments were repeated using melanoma G361 cells. Data are the means ± S.D. (n = 3). *, p < 0.05 versus nontreated control.